Active constituent

Route of administration

No.

Treated

No.

Affected

No.

Died

Reported Adverse Experience

Classification and comments

Monensin

Oral

Not recorded

1

1

Approximately three months after a herd of cattle were treated a bull was found dead, allegedly of bloat. The capsule was found to have completely paid out despite only being in the animal for 84 days.

Possibly product-related.

The product should continue to pay out for at least 100 days. The reason for the increased rate of pay out of this product is unknown.

Monensin

Oral

132

1

1

One steer out of a mob of 132 cattle treated was found dead allegedly of bloat, 64 days after being treated with this product. The product was found to have completely paid out.

Possibly product-related.

The product should continue to pay out for at least 100 days. The reason for the increased rate of pay out of this product is unknown.

Active constituent

Route of administration

No.

Treated

No.

Affected

No.

Died

Reported Adverse Experience

Classification and comments

Living attenuated distemper, canine adenovirus type 2, parvovirus type 2

Living canine parainfluenza virus

Subcutaneous

1

1

Nil

Dog was vaccinated at 10 weeks and 15 weeks of age with this vaccine. Thirteen months later the dog was presented with vomiting, anorexia, depression and profuse blood-stained diarrhoea. A blood test indicated that the dog was suffering from dehydration. A faecal test was positive for parvovirus. The dog recovered after intensive treatment.

Possibly product-related

Febantel, pyrantel embonate and praziquantel

Oral

9

9

Nil

Nine pups were treated at 2, 4, 6, 8 and 12 weeks of age with this product as a routine intestinal worm preventative. Five days after the last treatment was given, some of the pups collapsed. The attending veterinarian diagnosed hookworm infestation. The pups were subsequently treated with another worming product. All pups recovered.

Possibly product-related

In some instances where a heavy infestation is present or there are a large number of dogs in the household, more frequent worming is recommended. This is clearly outlined on the product label.

Other measures may be required to adequately control environmental burdens.

Active constituent

Route of administration

No.

Treated

No.

Affected

No.

Died

Reported Adverse Experience

Classification and comments

Praziquantel, pyrantel embonate and oxantel embonate

Oral

1

1

1

This dog was treated with this product since two weeks of age according to the label directions. At three months of age, the dog became unsteady on its legs, started salivating excessively and the oral mucous membranes were noted to be very pale (white). No post mortem was performed, although the cause of death was assumed to have been hookworm infestation based on the presence of hookworm eggs in the faeces.

Possibly product-related

In some instances where a heavy infestation is present or there is a large number of dogs in the household, more frequent worming is recommended. This is clearly outlined on the product label.

Other measures may be required to adequately control environmental burdens.

Febantel, pyrantel embonate and praziquantel

Oral

2

2

1

These two dogs were treated with this product for two months. The pups developed black faeces and started to vomit. The attending veterinarian diagnosed hookworm infestation. One pup died despite treatment. The second dog survived after receiving a blood transfusion.

Possibly product-related

In some instances where a heavy infestation is present or there is a large number of dogs in the household, more frequent worming is recommended. This is clearly outlined on the product label.

Other measures may be required to adequately control environmental burdens.

Active constituent

Route of administration

No.

Treated

No.

Affected

No.

Died

Reported Adverse Experience

Classification and comments

Fipronil

External

1

1

1

Nine days after this product was applied to a dog, it developed mild ataxia and was treated for tick paralysis. The attending veterinarian searched the dog and found one small, inactive tick. The dog improved and was sent home. Three days later the dog developed respiratory problems and was again hospitalised. One near-dead tick was found. The dog was given a second dose of tick antiserum and appeared to be recovering well. The following day the dog developed acute renal failure. It was given appropriate supportive therapy but died. The veterinarian felt that the dog may have had sub-clinical renal disease that was precipitated by the stress of tick paralysis.

Possibly product-related

The label of this product indicates clearly that searching the dog thoroughly each day is vital as ticks can attach and inject toxin before they are killed by this product, although this is rare.

Fipronil

External

1

1

1

A dog developed ataxia and respiratory problems three days after being treated with this product. It was hospitalised and treated for tick paralysis and improved after administration of tick antiserum. The condition of the dog deteriorated and it died three days later. The dog had also been treated for tick paralysis one week before this incident.

Possibly product-related

The label of this product indicates clearly that searching the dog thoroughly each day is vital as ticks can attach and inject toxin before they are killed by this product, although this is rare.

Active constituent

Route of administration

No.

Treated

No.

Affected

No.

Died

Reported Adverse Experience

Classification and comments

Fipronil

External

1

1

1

The owner used this product every 2 weeks on 3 dogs to control paralysis tick. One dog developed tick paralysis eleven days after treatment. Two ticks were found. The dog was treated with tick antiserum and recovered. A second dog also developed tick paralysis one day following treatment. It was hospitalised and treated with tick antiserum but died 12 hours later. Owner lives in a rural area with many bandicoots, which are the native host of the paralysis tick.

Possibly product-related.

The label of this product indicates clearly that searching the dog thoroughly each day is vital as ticks can attach and inject toxin before they are killed by this product, although this is rare.