Molinate

Molinate (ethyl N, N’-hexamethylenethiolocarbamate) is a pre and post-emergent, systemic thiocarbamate herbicide used exclusively in rice growing for the control of barnyard grasses (Echinochloa spp.) and silver top or brown beetle grass (Diplachne fusca).

Molinate review


Status: Review in progress

Update:

Molinate review process

This timeline provides an overview of the stages and dates of the molinate review. The review commenced in 2003.  A review scope document was published in 2003. In 2004, the APVMA received a toxicology assessment report for molinate, whilst the molinate review advisory committee was formed. Between 2004 and 2012 revised component reports for occupational health and safety, and environment were received and assessed.  In 2011, registrants voluntarily amended product labels for use in closed delivery and supply systems only to reduce worker exposure to molinate. In April 2013, the APVMA released the toxicological and occupational health and safety (OHS) assessments for molinate. These assessments did not support the ongoing ground or aerial application of molinate, based on human health concerns. After consideration of the component assessments of molinate (toxicology, revised OHS and environment), the APVMA will publish a preliminary review findings report that will outline the proposed final regulatory actions for molinate. Following consideration of any public comments, the APVMA will release the molinate review findings report which will finalise the review of molinate.

Background

In May 2003, the APVMA began a review of molinate because of toxicological, occupational health and safety and environmental concerns and released the Molinate Review Scope Document (PDF, 50Kb). The scope document outlined the information needed to conduct a comprehensive scientific assessment of molinate.

In June 2004, the Advisory Committee on Chemicals Scheduling (ACCS) reconsidered the scheduling of molinate. The ACCS included molinate in Schedule 7 of the Standard for the Uniform Scheduling of Medicines and Poisons (SUSMP) (external site).

In June 2011, registrants voluntarily amended product labels in a collaborative effort with the APVMA to reduce worker exposure to molinate. Molinate product labels were amended for use in closed delivery and supply systems only.

In June 2013, the APVMA released the toxicological and occupational health and safety (OHS) assessments for molinate in combination with a targeted consultation with affected industry and State departmental agencies. These assessments did not support the ongoing ground or aerial application of molinate, based on human health concerns.

In January 2014  the APVMA released the Molinate Preliminary Review Findings Report. This proposed the cancellation of all active constituent approvals, all product registrations and all product label approvals on the basis that products containing molinate may have an effect that is harmful to humans and compromise worker safety.

Molinate review archive


Title Date
Molinate Preliminary Review Findings (PDF, 555kb) | (DOC, 401kb) January 2014
Review of the mammalian toxicology and metabolism/toxicokinetics of molinate (PDF, 556Kb) | (RTF, 1.1Mb) June 2013
OHS risk assessment of the ground and aerial application of molinate (PDF, 253Kb) | (RTF, 769Kb) June 2013
Gazette notice: Reconsideration of approvals and registrations related to molinate May 2003
Molinate Scope Document (PDF, 50Kb) May 2003

Contact

For more information contact:

Chemical Review

Phone: +61 2 6210 4749

Fax: +61 2 6210 4776

Email: chemicalreview@apvma.gov.au

Product Search

Search the PUBCRIS database for registered products that contain molinate.
Note: In the Active Constituent 1 field enter molinate.

 

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