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Standard for methyl bromide active constituent
Version 1 August 20041. Description: the material shall consist of methyl bromide together with related manufacturing impurities and shall be a colourless, odourless gas, free from visible extraneous matter and added modifying agents.
2. Common Name: methyl bromide
3. Chemical Name (IUPAC): bromomethane
4. CAS Number: 74-83-9
5. Identity test: identity of the active constituent must be
established by one or more of the following methods: spectroscopic tests
(IR spectrum, NMR, mass spectra), Chromatography (HPLC or GC retention
time with reference compound) or any other suitable test method.
6. Composition
6.1 Active constituent: 950 g/kg minimum
7. Analytical methods
- The analytical method used for the determination of the active constituent and toxicological significant impurities must be validated in accordance with the APVMA guidelines for the validation of analytical methods.
- Collaboratively tested standard CIPAC and AOAC methods for the analysis for the active constituent and any method submitted as a part of the new active constituent application that has been accepted by the APVMA are regarded as validated and do not require revalidation.
- Unless the scope of the collaborative method (CIPAC and AOAC) also includes toxicological significant impurities in the active constituent, validation data for impurities are required.
AOAC: Association of Official Analytical Chemists (The Official Methods
of Analysis)
CIPAC: Collaborative International Pesticides Analytical Council